A-KETOGLUTARIC ACID, SODIUM SALT

A-KETOGLUTARIC ACID, SODIUM SALT - Names and Identifiers

Name	ALPHA-KETOGLUTARIC ACID MONOSODIUM SALT
Synonyms	sodium hydrogen 2-oxoglutarate A-KETOGLUTARIC ACID, SODIUM SALT 2-OXOGLUTARIC ACID MONOSODIUM SALT ALPHA-KETOGLUTARIC ACID SODIUM SALT 2-KETOGLUTARIC ACID MONOSODIUM SALT 2-OXOPENTANEDIOIC ACID MONOSODIUM SALT ALPHA-KETOGLUTARIC ACID MONOSODIUM SALT
CAS	22202-68-2
EINECS	244-836-6

A-KETOGLUTARIC ACID, SODIUM SALT - Physico-chemical Properties

Molecular Formula	C5H5NaO5
Molar Mass	168.08
Solubility	H2O: 0.5M at20°C, clear, colorless
Appearance	Powder
Color	White
BRN	4597521
Storage Condition	2-8°C
Physical and Chemical Properties	Bioactive 2-Ketoglutaric acid Sodium (Alpha-Ketoglutaric acid Sodium) is an intermediate product of the tricarboxylic acid cycle, and is simultaneously linked to glutamic acid and glutamine metabolism through transamination.
In vitro study	2-Ketoglutaric acid Sodium (Alpha-Ketoglutaric acid Sodium) has other physiological capabilities including reduction of ammonia level formed in the lung and general ammonia detoxification, protective role against lipid peroxidation and neuroprotective effect against cyanide poisoning. 2-Ketoglutaric acid Sodium acts as precursor for the synthesis of amino acids and nucleotides.

A-KETOGLUTARIC ACID, SODIUM SALT - Risk and Safety

Hazard Symbols	T - Toxic
Risk Codes	R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
WGK Germany	3
FLUKA BRAND F CODES	10

A-KETOGLUTARIC ACID, SODIUM SALT - Upstream Downstream Industry

Raw Materials	2-Ketoglutaric acid L-(+)Sodium glutamate
Downstream Products	PYRIDOXAMINE-5'-PHOSPHATE

A-KETOGLUTARIC ACID, SODIUM SALT - Security information

WGK Germany	3
F	10

Last Update：2024-04-10 22:29:15

A-KETOGLUTARIC ACID, SODIUM SALT - Uses and synthesis methods

target

Human Endogenous Metabolite

Tyrosinase

15 mM (IC 50 )

in vitro study

2-Ketoglutaric acid Sodium (Alpha-Ketoglutaric acid Sodium) has other physiological capabilities including reduction of ammonia level formed in the lung and general ammonia detoxification, protective role against lipid peroxidation and neuroprotective effect against cyanide poisoning.

2-Ketoglutaric acid Sodium acts as precursor for the synthesis of amino acids and nucleotides.

Last Update：2024-04-09 21:01:54

A-KETOGLUTARIC ACID, SODIUM SALT - Introduction

Sodium LPHA-ketoglutarate (also known as sodium α-ketoglutarate) is a white crystalline solid with the chemical formula C5H3O5Na and a relative molecular mass of 190.06g/mol. It is stable at normal temperature, but it is best to store it at a low temperature of 2-8°C.

LPHA-ketoglutarate sodium is widely used in the pharmaceutical and cosmetic industries. It is often used as a pain-relieving and anti-inflammatory drug, and can also be used to relieve the symptoms of arthritis and rheumatism. In addition, it can also be used as a moisturizer and antioxidant in skin care products.

Preparation of sodium LPHA-ketoglutarate is usually prepared by reacting ketoglutaric acid with sodium bicarbonate. Specific preparation methods can be found through scientific literature or consulting professional chemical laboratories.

Regarding safety information, LPHA-ketoglutarate sodium is generally considered to be a relatively safe compound. However, relevant safety measures still need to be taken during use and operation, such as wearing appropriate personal protective equipment, avoiding inhalation of dust, and avoiding contact with skin and eyes. In case of contact, immediately flush the affected area with plenty of clean water. Before use, it is recommended to read and follow the safety data sheet of the compound or the safety instructions provided by the relevant chemical supplier.

Last Update：2024-04-09 21:31:53

A-KETOGLUTARIC ACID, SODIUM SALT - Nature

storage conditions	2-8°C
solubility	H2O: 0.5 M at 20 °C, clear, colorless
morphology	Powder
color	White
BRN	4597521

Last Update：2024-04-10 22:29:15

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